Proactive and acne medication

« ...Retinoids Help Normalize KeratinizationAlthough the mechanism by which topical and systemic retinoids help restore acne follicles to a healthy state is unknown, it has been well demonstrated that they normalize keratinization within the infundibular region of the follicle, so that shed follicular cells slough to the surface of the skin rather than clump together and obstruct the pores.After exposure to retinoids, follicular cells actually turn over more rapidly than they would in a pre-acne state.Retinoic acid has a high affinity for the gamma retinoid receptors, which are believed to be integral to the pathogenesis of acne.In addition to their ability to reverse abnormal keratinization within the follicle, the topical retinoids - especially adapalene (Differin®), a naphthoic acid derivative - may have anti-inflammatory properties and thus may address two factors involved in the development of acne....
...Acne Causes - Culprit : Hormones. For the majority of acne sufferers, the trouble begins at puberty, when the body begins to produce hormones called androgens. These hormones cause the sebaceous glands to enlarge, which is a natural part of the body's development. In acne sufferers, however, the sebaceous glands are overstimulated by androgens, sometimes well into adulthood. Androgens are also responsible for acne flare-ups associated with the menstrual cycle and, on occasion, pregnancy....»
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«...But there is hope. While acne is not curable, it is treatable. We now know more about controlling this condition than ever before. The secret to managing acne is prevention — stopping this condition before it exhibits visual symptoms. Once you have found an acne treatment that helps you accomplish this, it's important to stick with it. Even after pimples disappear, you may need to continue treatment to keep new blemishes at bay. It's also crucial to begin treatment as soon as the first signs appear; the sooner you address your acne, the less likely you are to experience permanent damage to your skin. Of course, in order to stop acne, we must first find out how it starts....»
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